This site is intended for U.S. audiences only.

VORANIGO dosing

VORANIGO is a pill taken orally once daily with or without food.

The standard dose of VORANIGO is one 40 mg pill taken by mouth.

When taking VORANIGO, remember to:

Take VORANIGO exactly as your healthcare provider tells you

Do not change your dose or stop taking VORANIGO without talking to your healthcare provider

Take VORANIGO once a day, about the same time each day

Swallow VORANIGO pills whole with water. Do not split, crush, or chew the pills

Consult your doctor on determining the right treatment schedule for you. Your doctor can help answer any questions you may have about taking VORANIGO.

What if I miss a dose
of VORANIGO?

If you miss a dose of VORANIGO by less than 6 hours, take the missed dose right away. Take your next dose at your usual time

If you miss a dose by more than 6 hours, skip the dose for the day. Take your next dose at your usual time

If you vomit after taking VORANIGO, do not take an extra dose. Take your next dose at your usual time

How to store
VORANIGO

Store VORANIGO at room temperature between 68 °F and 77 °F (20 °C to 25 °C)

VORANIGO comes with desiccant canisters (drying agents) in the bottle to help keep the medicine dry (protect from moisture). Do not remove the desiccant canister from the bottle. Do not swallow the desiccant canister

The VORANIGO bottle has a child resistant cap. Keep VORANIGO and all medicines out of reach of children

Taking other medications while taking VORANIGO

Some medications may affect how VORANIGO works in your body, and VORANIGO may affect how other medications work in your body as well. Make sure to talk to your healthcare team about all the medications you take, including all over-the-counter medications, vitamins, and herbal supplements.

If you start any new medications while taking VORANIGO, inform all your healthcare professionals so they all have the most current list.

Learn about the possible side effects of taking VORANIGO

Learn more

ServierONE Patient Support Services

ServierONE offers patients helpful resources and tools for navigating treatment, costs, and education throughout their journeys, including a VORANIGO copay program.

For more information:

Visit

ServierONE.com

USPatientServices@servier.com

Call

1-800-813-5905

Monday-Friday, 8 AM to 8 PM ET

What is VORANIGO?

VORANIGO (40 mg tablets) is a prescription medicine used to treat adults and children 12 years of age and older with certain types of brain tumors called astrocytoma or oligodendroglioma with an isocitrate dehydrogenase-1 (IDH1) or isocitrate dehydrogenase-2 (IDH2) mutation, following surgery. Your healthcare provider will perform a test to make sure that VORANIGO is right for you. It is not known if VORANIGO is safe and effective in children under 12 years of age.

What are the possible side effects of VORANIGO?

VORANIGO may cause serious side effects, including:

Liver problems. Changes in liver function blood tests may happen during treatment with VORANIGO and can be serious. Your healthcare provider will do blood tests to check your liver function before and during treatment with VORANIGO. Tell your healthcare provider right away if you develop any of the following signs and symptoms of liver problems:

yellowing of your skin or the white part of your eyes (jaundice)

dark tea-colored urine

loss of appetite

pain on the upper right side of your stomach area

feeling very tired or weak

The most common side effects of VORANIGO include:

increased liver enzyme levels in the blood

lack of energy, tiredness

headache

COVID-19

muscle aches or stiffness

diarrhea

nausea

seizure

Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment with VORANIGO if you have certain side effects.

VORANIGO may affect fertility in females and males, which may affect the ability to have children. Talk to your healthcare provider if this is a concern for you.

These are not all of the possible side effects of VORANIGO.

Before taking VORANIGO, tell your healthcare provider about all of your medical conditions, including if you:

have liver problems

have kidney problems or are on dialysis

smoke tobacco

are pregnant or plan to become pregnant. VORANIGO can harm your unborn baby

Females who are able to become pregnant:

Your healthcare provider will do a pregnancy test before you start treatment with VORANIGO

You should use effective nonhormonal birth control during treatment with VORANIGO and for 3 months after the last dose. VORANIGO may affect how hormonal contraceptives (birth control) work and cause them to not work well. Talk to your healthcare provider about birth control methods that may be right for you during treatment with VORANIGO

Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with VORANIGO

Males with female partners who are able to become pregnant:

You should use effective birth control during treatment with VORANIGO and for 3 months after the last dose

Tell your healthcare provider right away if your partner becomes pregnant or thinks she may be pregnant during your treatment with VORANIGO

Tell your healthcare provider if you are breastfeeding or plan to breastfeed. It is not known if VORANIGO passes into breast milk. Do not breastfeed during treatment with VORANIGO and for 2 months after the last dose.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. VORANIGO may affect the way other medicines work, and other medicines may affect how VORANIGO works.

Please see Full Prescribing Information.